SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Nt5etm3(NT5E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200009
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd74em1(hCD74)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000082
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cd79bem2(hCD79B )Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000012
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd80em1(hCD80) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00074
Research Application：cancer research,immune system
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Strain Name：C57BL/6Smoc-Cd93em1(hCD93)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215065
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Strain Name：C57BL/6Smoc-Cd96em2(hCD96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000059
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cftrtm1(hCFTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225060
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00014
Research Application：cancer research,Immunotherapy,drug screening；
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Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190078
Research Application：Immunotherapy,cancer research,drug screening
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