EAE animal model

Protocol of inducing


6-8-week-old healthy female C57BL/6 mice were immunized by MOG35-55/CFA on day0. image.png

Validation data

image.png

image.png

Figure 1: MOG35-55 induced EAE model in C57BL/6  (A) body weight (B) clinical score (n=5).

image.png

Figure 2: MOG35-55 induced EAE model in C57BL/6 (A) typical pathology image (B) histological score (n=5), ***P < 0.001 vs G2.

image.png

Figure 3: MOG35-55 induced EAE model in C57BL/6 (A) LFB demyelination pathology image (B) LFB score (n=5), *** P < 0.001 vs G2.


热门文章