The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-PNPLA3 I148M-IRES-GFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200013
Research Application：rs738409：148 isoleucine to Methionine protein variant,I148M.Non-alcoholic fatty liver and hepatitis B cirrhosis research.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-240013
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200051
Research Application：Cancer and aging research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200052
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200048
Research Application：Cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210137
Research Application：Fluorescent reporter Mice
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SNCA A53T-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200320
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200263
Disease Connection：amyotrophic lateral sclerosis type 1
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200020
Research Application：Spontaneous skin cancer model
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-234153
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