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Models

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Mice

hSOST

Strain Name：C57BL/6Smoc-Sostem1(hSOST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200251

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Mice

hCD3E/hCD20(2)

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Ms4a1tm2 (hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220035

hCD3E(NM-HU-00114) mice were crossed with hCD20(2)(NM-HU-200114) to generate hCD3E/hCD20(2) mice.

Mice

hIL6/hIL6R

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Il6raem1(hIL6R)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190025

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

hSLAMF7

Strain Name：C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18028

The endogenous mouse Slamf7 gene was replaced by human SLAMF7 gene .

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

Trp63-DreERT2

Strain Name：C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190029

A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.

Mice

Hopx-2A-DreERT2

Strain Name：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Rorc-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204991

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

Mice

hCD3E/hLAG3

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220027

hCD3E(NM-HU-00114) was crossed with hLAG3( NM-HU-00049) to generate hCD3E/hLAG3 mice.

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