Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice	hSIGLEC8 Strain Name：C57BL/6Smoc-Siglece^{em1(hSIGLEC8)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-204983 Research Application：Immunotherapy, drug screening
Mice	hSIGLEC8(2) Strain Name：C57BL/6Smoc-Siglecf^{em1(hSIGLEC8)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-210033 Research Application：inmmue therapy；drug screening
Mice	hSIGLEC9 Strain Name：C57BL/6Smoc-Siglece^{em1(hSIGLEC9)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-HU-225072
Mice	hSIRPA(2) Strain Name：C57BL/6Smoc-Sirpa^{tm2(hSIRPA)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-18015 Research Application：Immunotherapy,drug screening
Mice	hSIRPA(2)/hCD47 Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd47^{em1(hCD47)/Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-2000111 Research Application：Immunotherapy,cancer research,drug screening
Mice	hSIRPA(2)/hCD47/hCTLA-4 Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd47^em1(hCD47)Ctla4^{em1(hCTLA4) Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-210368 Research Application：inmmue therapy;drug screening
Mice	hSIRPA(2)/hCD47/hPD-1 Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd47^em1(hCD47)Pdcd1^{em1(hPDCD1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-2000090 Research Application：Immune-related
Mice	hSIRPA(2)/hCD47/hPD-1/hPD-L1 Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd47^em1(hCD47)Pdcd1^em1(hPDCD1)Cd274^{em1(hPD-L1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-210358 Research Application：inmmue therapy；drug screening
Mice	hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd47^em1(hCD47)Pdcd1^em1(hPDCD1)Cd274^{em2(hPD-L1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-220029
Mice	hSIRPA(2)/hCD47/hPD-L1 Strain Name：C57BL/6Smoc-Sirpa^tm2(hSIRPA)Cd274^em1(hCD274)Cd47^{em1(hCD47)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-2000095 Research Application：Immunotherapy,cancer research,drug screening

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