Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Ripk1tm1(hRIPK1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233240
Mice
Strain Name:C57BL/6Smoc-Ror1tm(hROR1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230014
Mice
Strain Name:C57BL/6Smoc-Ror2em(hROR2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230017
Mice
Strain Name:C57BL/6Smoc-Rspo1tm1(hRSPO1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225041
Mice
Strain Name:C57BL/6Smoc-Rspo3tm1(hRSPO3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234377
Mice
Strain Name:C57BL/6Smoc-Rtn4tm1(hRTN4)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234375
Mice
Strain Name:C57BL/6Smoc-Rtn4rem1(hRTN4R)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234373
Mice
Strain Name:C57BL/6Smoc-Rxfp1em1(hRXFP1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234263
Mice
Strain Name:C57BL/6Smoc-Scapem1(hSCAP)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232854
Mice
Strain Name:C57BL/6Smoc-Scn9atm1(hSCN9A)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232904
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