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Models

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Mice

hKITLG(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Kitlem1(hKITLG)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000039

The endogenous mouse Kitl gene was replaced by human KITLG gene.

Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E))Cd38em2(hCD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

Mice

hPD-L1/hCD73(2)

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Nt5eem2(NT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210356

hPD-L1(NM-HU-00062) was crossed with hCD73(2)(NM-HU-200009) to generate hPD-L1/hCD73(2) mice.

Mice

Drd1-2A-CreERT2

Strain Name：C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18016

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hVEGFR2

Strain Name：C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00098

The endogenous mouse Kdr gene was replaced by human KDR gene .

Mice

H11-CAG-LSL-mtagBFP2

Strain Name：C57BL/6Smoc-lgs2em1(CAG-LSL-mTagBFP2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190006

A CAG-LSL-mTagBFP2-3xFLAG-WPRE-polyA cassette was inserted at the mouse H11 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the mTagBFP2-3xFLAG protein.

Mice

CD8a-IRES-Luc-2A-tdTomato（BALB/c）

Strain Name：BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200208

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

Axl-KO

Strain Name：C57BL/6Smoc-Axlem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200044

Exon 3 of Axl gene was deleted to generate Axl knockout mice.

Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9em2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hCTLA-4/h4-1BB(2)

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210355

hCTLA4(NM-HU-00014) was crossed with h4-1BB(2)(NM-HU-190077）to generate hCTLA4/h4-1BB(2) mice.

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