Welcome to Advanced Search

Models

About 42,518 results
Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

hCCR8/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210435

hCCR8(NM-HU-190053) was crossed with hCTLA4(NM-HU-00014) to generate hCCR8/hCTLA4 mice.

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1tm2 (hCD20)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200114

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

Muc2-2A-CreERT2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Muc2em1(2A-CreERT2-tdTomato-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200301

2A-CreERT2-tdTomato-Wpre-pA expression cassette was knocked into the Muc2 gene stop codon site.

Mice

Aicda-Cre

Strain Name：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200160

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

Itgax-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Itgaxem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204992

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Itgax gene .

Mice

hSEMA4D

Strain Name：C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

Mice

hCD24/hSIGLEC10

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210367

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061）to generate hCD24/hSIGLEC10 mice.

Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Email Back to top