Npr3-2A-DreERT2

Nomenclature

C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190015

Strain State

Repository Live

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Model Description

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the heart of Npr3DreERT2/+；R26ZsGreen/+ mouse. ZsGreen (green) expression can be detected in the heart after tamoxifen treatment. Fabp4 (tdTomato) is the marker gene known to be expressed in the coronary vessel endothelial cells. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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