Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hMSLN-IRES-Luciferase-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225094
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-HA-hMYCN-IRES-BFP-Wpre-polyA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225000
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190077
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18050
Research Application：Tumor research; drug screening
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065
Disease Connection：breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215002
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200051
Research Application：Cancer and aging research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200052
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200048
Research Application：Cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200020
Research Application：Spontaneous skin cancer model
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