hCSF2RB/hIL3/hCSF2

Nomenclature

C57BL/6Smoc-Csf2rbtm(hCSF2RB)Il3tm(hIL3)Csf2tm(hCSF2)Smoc

Cat. NO.

NM-HU-230239

Strain State

Developing

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Gene Summary

Gene Symbol
IL3

Gene Symbol
CSF2

Gene Symbol
Csf2rb

Model Description

hCSF2RB(NM-HU-225078)was crossed with hIL3/hCSF2(NM-HU-190065)to generate hCSF2RB/hIL3/hCSF2.

Validation Data

image.png

Fig.1 Detection of CSF2RB expression in mammary gland by RT-PCR (6-8wks, female). 

Wild type: only one band at 517 bp with primers F1/R1(mCsf2rb);

Homozygous: only one band at 324 bp with primers F2/R2(hCSF2RB).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCD131 expression on B cells and Granulocytes in Bone marrow in hCSF2RB/hIL3/hCSF2 tKI mice.

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Fig.3 Detection of hCD131 expression on B cells and Granulocytes in Spleen in hCSF2RB/hIL3/hCSF2 tKI mice.


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