Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Tnfsf12/Tnfsf13tm1(hTNFSF12/hTNFSF13)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-234421
Mice
Strain Name:C57BL/6Smoc-Ugt1a1tm1(hUGT1A1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232902
Mice
Strain Name:C57BL/6Smoc-Uhrf1em1(hUHRF1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-240157
Mice
Strain Name:huHSC-(NMG)
Strain State:Repository Live | Cat. NO.:NM-NSG-017
Research Application:Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study
Mice
Strain Name:huPBMC-(NMG)
Strain State:Repository Live | Cat. NO.:NM-NSG-015
Research Application:Infectious disease; Gene therapy;Hematopoiesis; Drug targets without cross-reactivity; Immunogenicity study
Mice
Strain Name:C57BL/6Smoc-Vegfatm1(hVEGFA)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000028
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Vegfaem1(hVEGFA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-204984
Mice
Strain Name:C57BL/6Smoc-Vegfctm(hVEGFC)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230016
Mice
Strain Name:C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00098
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Kdrtm2(hKDR) Smoc
Strain State:Developing | Cat. NO.:NM-HU-232384
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