hIL2RA/hIL2RB/hIL2RG

Nomenclature

C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc

Cat. NO.

NM-HU-210414

Strain State

Embryo cryopreservation

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Model Description

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

Validation Data

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Fig1. Detection of IL2RA expression in thymus and spleen by RT-PCR. Wild type: only one band at 350 bp with primers F1/R1(mIl2ra);Homozygous: only one band at 318 bp with primers F2/R2(hIL2RA); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of IL2RB expression in thymus and spleen by RT-PCR. Wild type: only one band at 360 bp with primers F1/R1(mIl2rb);Homozygous: only one band at 281 bp with primers F2/R2(hIL2RB); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig3. Detection of IL2RG expression in thymus and spleen by RT-PCR. Wild type: only one band at 400 bp with primers F1/R1(mIl2rg);Homozygous: only one band at 263 bp with primers F2/R2(hIL2RG); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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