R26-CAG-LSL-GqDREADD(hM3Dq)-2A-mCitrine

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GqDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA)Smoc

Cat. NO.

NM-KI-190106

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Synonyms

R26，ROSA26，AV258896，Gtrgeo26，Gtrosa26，Thumpd3as1

NCBI ID

14910

MGI ID

104735

Ensembl ID

ENSMUSG00000086429

Pubmed

Gt(ROSA)26Sor

Model Description

These mice harbor a CAG-LSL-HA-GiDREADD（hM3Dq)-P2A-mCitrine-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.
Research Application：Chemical Genetics studies.The GqDREADD(hM3Dq) could stimulate the activity of neurons following administration of CNO.

Validation Data

hM3Dq.png

Fig1. Expression Pattern of Citrine in the brain of Dppa3-Cre+/-;R26-hM3Dq-2A-mCitrine+/-  mice.

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