hINHBE

Nomenclature

C57BL/6Smoc-Inhbeem1(hINHBE)Smoc

Cat. NO.

NM-HU-233512

Strain State

Repository Live

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Gene Summary

Gene Symbol
Inhbe

Model Description

The endogenous mouse Inhbe gene was replaced by human INHBE gene.


Validation Data

image.png

Fig.1 Detection of INHBE expression in liver by RT-PCR. 

Wild type: only one band at 192 bp with primers F1/R1 (mInhbe);

Homozygous: only one band at 217 bp with primers F2/R2 (hINHBE).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human INHBE expression in liver in hINHBE knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, Hep G2 cells.

Note. The anti-human INHBE Antibody cross-reacted with mouse INHBE and humanized INHBE. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.

image.png

Fig.3 Detection of hINHBE expression in serum by ELISA (n=3).

Note. The human INHBE Elisa kit cross-reacted with mouse INHBE and humanized INHBE.



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