U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190080
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190007
Research Application:cancer
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR3(K562E)-IRES-Luciferase-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190081
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR3(S249C)-IRES-Luciferase-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190082
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR3-IRES-Luciferase-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190083
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-ERBB2(exon20 insertion)-IRES-Luciferase-2A-EGFP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190071
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190008
Research Application:cancer
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190074
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190075
Disease Connection:D-2-hydroxyglutaric aciduria
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190076
Research Application:cancer research
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