The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-LSL-Kozak-hPROCR-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-240013
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200051
Research Application:Cancer and aging research
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200052
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200048
Research Application:Cancer research
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SIGLEC8-IRES-EGFP-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210137
Research Application:Fluorescent reporter Mice
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SNCA A53T-IRES-EGFP-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200320
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200263
Disease Connection:amyotrophic lateral sclerosis type 1
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200020
Research Application:Spontaneous skin cancer model
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-234153
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Mice
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Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200019
Research Application:Amyotrophic lateral sclerosis(ALS) and frontotemporal lobar degeneration research
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