NVG-hIL15
Nomenclature
NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
Cat. NO.
GM-NVG-210001
Strain State
Repository Live
Gene Summary
Gene Symbol
Il15
Model Description
The endogenous mice Il15 gene was replaced by human IL15 gene.
Validation Data
Human IL15 expression analysis
Fig 1. Human IL15 expression analysis in homozygous NVG-hIL15 mice by ELISA.
Fig 2. Humanized immune reconstitution levels and body weight growth curves in huPBMC-NVG-hIL15 mice.
Fig 3. Humanized immune reconstitution levels and body weight growth curves in huPBNK-NVG-hIL15 mice.
Fig 4. Efficacy evaluation of CD20-targeting antibody using Raji huPBNK model.
Fig 5. Functional protein detection in NK cells in the presence of anti-hCD20 antibody drug using Raji huPBNK model.
Fig 6. ADCC efficacy research in vitro using huPBNK model.
Fig 7. Body weight growth curves in γδT-NVG-hIL15 mice.
Fig 8. Survial rates in γδT-NVG-hIL15 mice.
Fig 9. Humanized immune reconstitution levels in γδT-NVG-hIL15 mice.
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