U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210016
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-Nr3c1tm1(hNR3C1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225058
Mice
Strain Name:C57BL/6Smoc-Ntrk1em(hNTRK1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230058
Mice
Strain Name:C57BL/6Smoc-Olr1tm(hOLR1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230107
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00062
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190039
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210370
Research Application:inmmue therapy;drug screening
Mice
Strain Name:BALB/cAnSmoc-Cd274em(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220028
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200274
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210019
Research Application:tumor research;inmmue therapy;drug screening
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