hCD40L

Nomenclature

C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc

Cat. NO.

NM-HU-2000033

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Cd40lg

Synonyms

IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5; Tnlg8b

NCBI ID

21947

MGI ID

88337

Ensembl ID

ENSMUSG00000031132

Pubmed

Cd40lg

Human Ortholog

CD40L

Model Description

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.
Research Application：Immunotherapy,drug screening

Validation Data

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Fig1. Detection of hCD40L expression on Monocytes and Lymphocytes in hPBMC.

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Fig2. Detection of hCD40L expression on CD4+ T cells in Blood, Spleen and Bone Marrow in hCD40L KI mice.

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