hIGHG1

Nomenclature

C57BL/6Smoc-Ighg1tm1(hIGHG1)Smoc

Cat. NO.

NM-HU-225091

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ighg1

Synonyms

IgG1 Igh-4

NCBI ID

16017

MGI ID

96446

Ensembl ID

ENSMUSG00000076614

Pubmed

Ighg1

Human Ortholog

Null

Model Description

The endogenous mouse Ighg1 gene was replaced by human IGHG1 gene.

Validation Data

image.png

Fig.1 Detection of IGHG1 expression in lung by RT-PCR (8-9wks, male). 

Wild type: only one band at 298 bp with primers F1/R1 (mIghg2c);

Homozygous: only one band at 377 bp with primers F2/R2 (hIGHG1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hIGHG1 expression in serum by ELISA (HO: 6wks, WT: 8-12wks, male, n=3).

Abbr. HO, homozygous; WT, wild type.

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