hDMPK
Nomenclature
C57BL/6Smoc-Dmpktm1(hDMPK)Smoc
Cat. NO.
NM-HU-225084
Strain State
Repository Live
Gene Summary
Gene Symbol
Dmpk
Model Description
The endogenous mouse Dmpk gene was replaced by human DMPK gene.
Validation Data
Fig.1 Detection of DMPK expression in heart by RT-PCR.
Wild type: only one band at 259 bp with primers F1/R1(mDmpk);
Homozygous: only one band at 324 bp with primers F2/R2(hDMPK).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human DMPK expression in hDMPK knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous; PC, hela cells.
Note. The anti-human DMPK antibody cross-reacted with mouse DMPK and humanized DMPK. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.
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