R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrine

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)Smoc

Cat. NO.

NM-KI-190093

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Model Description

These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.
Research Application:Chemical Genetics studies.The inhibitory GiDREADD(hM4Di) could silence the activity of neurons following administration of CNO.

Validation Data

hM4Di.png

Fig1. Expression Pattern of Citrine in the brain of Dppa3-Cre+/-;R26-hM4Di-2A-mCitrine+/-  mice.


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