hTARDBP

Nomenclature

C57BL/6Smoc-Tardbptm(hTARDBP)Smoc

Cat. NO.

NM-HU-230026

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Tardbp

Synonyms

Tdp43; C85084; TDP-43; 1190002A23Rik

NCBI ID

230908

MGI ID

2387629

Ensembl ID

ENSMUSG00000041459

Pubmed

Tardbp

Human Ortholog

TARDBP

Model Description

The endogenous mouse Tardbp gene was replaced by human TARDBP gene.

Validation Data

image.png

Fig.1 Detection of TARDBP expression in bladder by RT-PCR. 

Wild type: only one band at 247 bp with primers F1/R1(mTardbp);

Heterozygous: one band at 247 bp with primers F1/R1(mTardbp) and one band at 296 bp with primers F2/R2(hTARDBP). 

Abbr. M, DNA marker;  HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human TARDBP expression in brain in hTARDBP knockin mice by WB. 

Abbr. HE,heterozygous; WT, wild type; M, marker.

Note: The anti-human TARDBP antibody cross-reacted with mouse TARDBP and humanized TARDBP.

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