SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221
Disease Connection：familial Mediterranean fever
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Strain Name：C57BL/6Smoc-Tg(pAlb-hAPOB)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225002
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Strain Name：C57BL/6Smoc-Tgtn(pAlb-hAPOB-WPRE-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-234136
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Strain Name：C57BL/6Smoc-Tgtn(pAlb-hAPOB-3’UTR-pA-pAlb-hLPA-3’UTR-pA)1Smoc(V2)
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-231783
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Strain Name：C57BL/6Smoc-Tg(pAlb-hAPOB-WPRE-pA-pAlb-hLPA-WPRE-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-232197
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Strain Name：C57BL/6Smoc-Tg(pAlb-hLPA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-225001
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Strain Name：C57BL/6Smoc-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-231782
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Strain Name：C57BL/6Smoc-Tg(pAlb-hLPA-WPRE-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-232196
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215053
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190127
Research Application：Chronic Myelocytic Leukemia(CML) research
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