Rag2-KO/hVEGFR2
Nomenclature
C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
Cat. NO.
NM-HU-200280
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Rag2
Gene Symbol
KDR
Model Description
Validation Data
Fig1. In vivo anti-tumor response of Cyramza and Avastin in the treatment of gastric cancer PDX model(GA2419)in the immunodeficient Rag2-KO/hKDR mice. (Completed in collaboration with CrownBio)
(A)Breeding scheme for development of Rag2-KO/hKDR mice; (B) Tumor growth curves upon treatment of Cyramza and Avastin; (C) Body weight change upon treatment.
Fig2. In vivo anti-tumor response of Cyramza in thetreatment of liver cancer PDX model(LI0612)in the im-munodeficient Rag2-KO/hKDR mice. (Completed in collaboration with CrownBio)
(A)Tumor blood vesselstaining via anti-human VEGFR2 IHC; (B) Tumor growth curves upon Cyramza treatment; (C)Body weight change upon treatment.
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