hVEGFR2
Nomenclature
C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Cat. NO.
NM-HU-00098
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
KDR
Model Description
Validation Data
Figure 1. Expression of mouse KDR and human KDR in C57BL/6 wild type mice and KDR-HU homozygous mice.
Figure 2:In vivo validation of anti-tumor efficacy in a B16F1 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor, demonstrating that the humanized KDR mice are a good in vivo model for validating the efficacy of drugs targeting human KDR.
Figure 3:In vivo validation of anti-tumor efficacy in a MC38 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more