R26-CAG-LSL-hACE2-IRES-tdTomato

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc

Cat. NO.

NM-KI-200188

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Synonyms

R26，ROSA26，AV258896，Gtrgeo26，Gtrosa26，Thumpd3as1

NCBI ID

14910

MGI ID

104735

Ensembl ID

ENSMUSG00000086429

Pubmed

Gt(ROSA)26Sor

Model Description

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.
Research Application：corona virus related research

Validation Data

R26-(CAG-LSL-human ACE2-IRES-tdTomato).png

Fig1 Western blot analysis of  human ACE2  protein expression in the tamoxifen-treated R26-CreERT2+/-  ; R26-hACE2+/- mice. 

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