hCLDN6
Nomenclature
C57BL/6Smoc-Cldn6em1(hCLDN6)Smoc
Cat. NO.
NM-HU-225034
Strain State
Repository Live
Gene Summary
Gene Symbol
Cldn6
Model Description
The endogenous mouse Cldn6 gene was replaced by human CLDN6 gene.
Validation Data
Fig.1 Detection of CLDN6 expression in lung by RT-PCR.
Wild type: only one band at 304 bp with primers F1/R1(mCldn6);
Homozygous: only one band at 141 bp with primers F2/R2(hCLDN6).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human CLDN6 expression in hCLDN6 knockin Mice by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous.
Note. The anti-human CLDN6 Antibody cross-reacted with mouse CLDN6 and humanized CLDN6.
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