hB7H3

Nomenclature

C57BL/6Smoc-Cd276tm2(hB7H3)Smoc

Cat. NO.

NM-HU-00107

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
CD276

Model Description

The endogenous mouse Cd276 gene was replaced by human CD276 gene.
Research Application:cancer research,Immunotherapy,drug screening

Validation Data

image.png

Fig1.Detection of hB7H3 Expression in Blood-derived Macrophages and DCs in hB7H3 KI Mice

image.png

Fig2.Detection of hB7H3 Expression in Spleen-derived Macrophages and DCs in B7H3 KI Mice

image.png

Fig3.Detection of hB7H3 Expression in Bone Marrow-derived Macrophages and DCs in hB7H3 KI Mice

image.png

Fig4.hB7H3 Expression Cahraterization in Liver-derived Endothelial Cells (CD11b- CD31+) in hB7H3 KI Mice

image.png

Fig5.hB7H3 Expression Cahraterization in Lung-derived Endothelial Cells (CD45- CD31+) in hB7H3 KI Mice

image.png

Fig6.hB7H3 Expression Detection in Testis-derived Endothelial Cells (CD45- CD31+) in hB7H3 KI Mice


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more