hPD-1/hCTLA-4(BALB/c)
Nomenclature
BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Cat. NO.
NM-HU-200277
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
CTLA4
Gene Symbol
Pdcd1
Model Description
Validation Data
Fig 1.In vivo efficacy study in PD1 & CTLA4 humanized mice. Keytruda, Opdico or Yervoy can inhibit the growth of CT26-hCD274 xenografts. The above data indicated that the hPD1/hCTLA4 humanized mouse is an effective model for antineoplastic drug screening.
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