hPD-1/hICOS(2)

Nomenclature

C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc

Cat. NO.

NM-HU-2000100

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
ICOS

Synonyms

AILIM; CCLP; CRP-1; H4; Ly115

NCBI ID

54167

MGI ID

1858745

Ensembl ID

ENSMUSG00000026009

Pubmed

ICOS

Human Ortholog

ICOS

Gene Symbol
Pdcd1

Synonyms

PD-1; Pdc1; Ly101

NCBI ID

18566

MGI ID

104879

Ensembl ID

ENSMUSG00000026285

Pubmed

Pdcd1

Human Ortholog

PDCD1

Model Description

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig1. Detection of PD1 expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

image.png

Fig2. Detection of human ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

image.png

Fig3. Detection of mouse ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.


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