hCCR8(2)/hCTLA-4

Nomenclature

C57BL/6Smoc-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)Smoc

Cat. NO.

NM-HU-220074

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CCR8

Synonyms

Cmkbr8

NCBI ID

12776

MGI ID

1201402

Ensembl ID

ENSMUSG00000042262

Pubmed

CCR8

Human Ortholog

CCR8

Gene Symbol
CTLA4

Synonyms

Cd152; Ly-56; Ctla-4

NCBI ID

12477

MGI ID

88556

Ensembl ID

ENSMUSG00000026011

Pubmed

CTLA4

Human Ortholog

CTLA4

Model Description

hCTLA4 (NM-HU-00014) mice were crossed with hCCR8(2) (NM-HU-2000054) mice to generate hCCR8(2)/hCTLA4 mice．

Validation Data

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Fig1. Statistics of hCCR8 and hCTLA-4 expression in hCCR8(2)/hCTLA-4 dKI mice.

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Fig2. Detection of hCCR8 and CTLA-4 expression on T cells in Tumor in hCCR8(2)/hCTLA-4 dKI mice.

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Fig3. Detection of hCCR8 and hCTLA-4 expression on T cells in Spleen in hCCR8(2)/hCTLA-4 dKI mice.

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