hCD3E/hPD-L1

Nomenclature

C57BL/6Smoc-Cd3eem1(hCD3E)Cd274em1(hPD-L1)Smoc

Cat. NO.

NM-HU-210449

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CD3E

Gene Symbol
Cd274

Model Description

hCD3E(NM-HU-00114) was crossed with hPD-L1(NM-HU-00062) to generate hCD3E/hPD-L1 mice

Validation Data

image.png

Fig1. Detection of CD3E expression in spleen and thymus by RT-PCR. Wild type: only one band at 465 bp with primers F1/R1(mCd3e);Homoygous: one band at 516 bp with primers F1/R1(recombinant hCD3E) and one band at 277 bp with primers F2/R2(hCD3E); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of PD-L1 expression in spleen and thymus by RT-PCR. Wild type: only one band at 347 bp with primers F1/R1(mPd-l1);Homoygous: only one band at 329 bp with primers F2/R2(hPD-L1); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.


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