hCD40/h4-1BB(2)
Nomenclature
C57BL/6Smoc-Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Cat. NO.
NM-HU-200256
Strain State
Repository Live
Gene Summary
Gene Symbol
CD40
Gene Symbol
Tnfrsf9
Model Description
Validation Data
Fig1. In vivo validation of double humanized CD40&4-1BB mice. Double humanized mice were inoculated with B16F10 cells, and randomly assigned to different groups (n=6) when the tumor grew to a volume of 80 mm3. A combinatorial treatment of anti-CD40 and anti-4-1BB inhibited tumor growth (top) without affecting the animal body weight (Bottom).
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