hSIRPA(2)

Nomenclature

C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc

Cat. NO.

NM-HU-18015

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Sirpa

Synonyms

Bit， P84， SIRP， SHP-1， CD172a， Ptpns1， SHPS-1， AI835480

NCBI ID

19261

MGI ID

108563

Ensembl ID

ENSMUSG00000037902

Pubmed

Sirpa

Human Ortholog

SIRPA

Model Description

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.
Research Application：Immunotherapy,drug screening

Validation Data

sirpa 流式.png

Figure 1. Detection of SIRPA expression in peripheral blood cells of humanized SIRPA mice.The FACS results of peripheral blood cells showed that the active expression of humanized SIRPA was detected in B cells and macrophage cells collected from heterozygous humanized SIRPA mice.(Completed in collaboration with CrownBio).

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