hCD3EDG
Nomenclature
C57BL/6-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Cat. NO.
NM-HU-220120
Strain State
Repository Live
Gene Summary
Gene Symbol
CD3E
Gene Symbol
CD3D
Gene Symbol
CD3G
Model Description
Validation Data
Fig 1. Expression detection of human CD3E/CD3D/CD3G by FACS in homozygous hCD3EDG mice.
Fig 2. Homozygous hCD3EDG mice were engrafted with MC38-hCLDN18.2 to eveluate the in vivo efficacy of anti-CD3×Claudin18.2 bispecific antibody in parallel with homozygous hCD3EDG mice.
Fig 3. Homozygous hCD3EDG mice were engrafted with MC38-hEpCAM to eveluate the AICD and irAE of OKT3 and anti-CD3×EpCAM bispecific antibody in vivo.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
