SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190011
Research Application：Immune-related
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Strain Name：BALB/cAnSmoc-Cd28em(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220509
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Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Cd38em2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-232307
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Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Folh1em1(hPSMA-Wpre-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-233160
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Strain Name：C57BL/6Smoc-Cd300ldem1(hCD300LD)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-234133
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Strain Name：C57BL/6Smoc-Cd33em3(CD33)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200002
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd37em1(hCD37)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225029
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Strain Name：C57BL/6Smoc-Cd38em2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190059
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Research Application：Immunotherapy,cancer research,drug screening
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