U-GEMMs

Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200267
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200264
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) Pvrigem1(hPVRIG)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-231147
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Sema4dem1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000093
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Sirpatm2(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000089
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Tmem173tm1(hTMem173)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000104
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00104
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Tigitem1(hTIGIT) Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190029
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00103
Research Application:Immunotherapy,cancer research,drug screening
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