hTIGIT(BALB/c,3)

Nomenclature

C.B6-Tigittm3(hTIGIT)Smoc

Cat. NO.

NM-HU-234664

Strain State

Developing

Export PDF

Gene Summary

Gene Symbol
TIGIT

Model Description

The hTIGIT(3)(NM-HU-200244) mice were backcrossed to BALB/c genetic background, to create the new strain of hTIGIT(BALB/c,3)(NM-HU-234664) mice.

Validation Data

image.png

Fig.1 Detection of TIGIT expression in large intestine by RT-PCR. 

Wild type: only one band at 229 bp with primers F1/R1(mTigit);

Homozygous: only one band at 168 bp with primers F2/R2(hTIGIT).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTIGIT expression on CD8+ T cells in hTIGIT KI mice. 

Note. Splenocytes from BALB/c and homozygous hTIGIT mice were stimulated with ConA in vitro.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more