U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190017
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00079
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200277
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) Erbb2tm1(hHER2)Smoc
Strain State:Repository Live | Cat. NO.:NM-XA-234902
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Icosem1(hICOS)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000100
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210018
Research Application:tumor research;inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00101
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200258
Research Application:tumor research;inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00108
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00100
Research Application:Immunotherapy,cancer research,drug screening
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