Isl1-CreERT2

Nomenclature

C57BL/6Smoc-Isl1em1(CreERT2) Smoc

Cat. NO.

NM-KI-00013

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Isl1

Synonyms

-

NCBI ID

16392

MGI ID

101791

Ensembl ID

ENSMUSG00000042258

Pubmed

Isl1

Human Ortholog

ISL1

Model Description

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.
Research Application：Cre recombinase tool

Validation Data

image.png

Fig. 1 CreERT2-mediated recombination in the heart of Isl1CreERT2/+；R26tdtomato/+ mouse embryo at E13.5. The Isl1+ cell lineage (tdTomato) mainly contributes to the right ventricle at E13.5 of Isl1CreERT2/+；R26tdtomato/+. Tamoxifen was induced at E8.0. (Documented in the following reference.)


Publications

Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases
References：Circulation

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