Ly6g-Cre-2A-tdTomato

Nomenclature

C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc

Cat. NO.

NM-KI-200219

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ly6g

Model Description

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.
Research Application:Cre tool mice

Validation Data

image.pngFig1. Cre mediated recombination in spleen of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse.

image.png

Fig2. Detection of tdTomato(red) and zsGreen(green) in various tissues of Ly6gCre-tdTomato/+;Rosa26zsGreen/+ mouse. Expression tissues include: spleen, thymus, colon. A few cells expressed in liver, stomach, kidney, small intestine and adrenal gland. Tissues that unexpressed include brain, spinal cord, eyeballs, heart, lung, salivary glands, brown fat, pituitary gland, pancreas, uterus and ovaries, muscle, skin. (5-week old, female) 

No obvious positive signals were detected in the tissue for tdTomato. (For more detailed information please contact our technical advisor.)

image.pngFig3. Detection of Ly6G and tdTomato expression on neutrophils in peripheral blood in WT and HE Ly6g-Cre-2A-tdTomato KI mice. 


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