Lgr5-2A-DreERT2

Nomenclature

C57BL/6Smoc-Lgr5em1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-200178

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Lgr5

Synonyms

FEX; Gpr49

NCBI ID

14160

MGI ID

1341817

Ensembl ID

ENSMUSG00000020140

Pubmed

Lgr5

Human Ortholog

LGR5

Model Description

A 2A-DreERT2 expression cassette was knocked into the Lgr5 gene stop codon site.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Glutamine synthetase (GS, green) is expressed in a rim of hepatocytes surrounding hepatic veins. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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