Il22-Cre

Nomenclature

C57BL/6Smoc-Il22em1(Linker-iCre-PolyA(SV40)Smoc

Cat. NO.

NM-KI-200167

Strain State

Repository Live

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Gene Summary

Gene Symbol
Il22

Synonyms

IL-22; Iltif; IL-22a; ILTIFa

NCBI ID

50929

MGI ID

1355307

Ensembl ID

ENSMUSG00000074695

Pubmed

Il22

Human Ortholog

IL22

Model Description

A Linker-iCre-PolyA expression cassette was knocked into the Il22 gene start codon site.
Research Application：The cytokine interleukin-22 (IL-22) plays an important role in tissue regeneration and maintenance of skin and mucosal barriers．

Validation Data

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Fig. 1 CreERT2-mediated recombination in the intestine of IL22Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the lymph nodes of IL22Cre/+; Rosa26tdTomato/+ mouse. 

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of IL22Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the lymph nodes of thymus, intestine and individual cells of testicular interstitium and cerebral cortex. TdTomato can not be detected in the kidney, heart, lung and liver. (For more detailed information please contact our technical advisor.)


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