Pgr-Cre

Nomenclature

C57BL/6Smoc-Pgrem1(iCre-WPRE-pA)Smoc

Cat. NO.

NM-KI-200117

Strain State

Repository Live

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Gene Summary

Gene Symbol
Pgr

Synonyms

PR; PR-A; PR-B; NR3C3; BB114106; 9930019P03Rik

NCBI ID

18667

MGI ID

97567

Ensembl ID

ENSMUSG00000031870

Pubmed

Pgr

Human Ortholog

PGR

Model Description

A iCre-WPRE-pA expression cassette was knocked into the Pgr gene start codon site.
Research Application：Cre recombinase tool

Validation Data

Pgr-(iCre)-1.png

Figure 1：Cre-mediated recombination in the brain, uterus, ovary, and oviduct of PgriCre/+; Rosa26tdTomato/+ mouse. Detection of tdTomato (red) in the brain, uterus, ovary, and oviduct of PgriCre/+; Rosa26tdTomato/+  mouse.

Pgr-(iCre)-2.png

Figure 2: Detection of tdTomato (red) in various tissues of PgriCre/+; Rosa26tdTomato/+ mice.

Reference(s)

METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor
References：PNAS

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