Ccr2-2A-DreERT2

Nomenclature

C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc

Cat. NO.

NM-KI-200023

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Ccr2

Synonyms

Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2

NCBI ID

12772

MGI ID

106185

Ensembl ID

ENSMUSG00000049103

Pubmed

Ccr2

Human Ortholog

CCR2

Model Description

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the liver of Ccr2DreERT2/+；R26tdTomato/+ mouse. TdTomato (red) expression can be detected in the liver after tamoxifen treatment. The F4/80 molecule is a unique marker of murine macrophages. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more