Foxp3-IRES-tdTomato-2A-Cre
Nomenclature
C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Cat. NO.
NM-KI-190119
Strain State
Repository Live
Gene Summary
Gene Symbol
Foxp3
Model Description
Validation Data
Fig1. Detection of tdTomato expression in C57BL/6 and HO Foxp3-IRES-tdTomato-2A-Cre mice.
Fig2. Cre-mediated recombination in the spleen and thymus of Foxp3Cre/+; Rosa26Zsgreen/+ mouse. Zsgreen(green) expression can be detected in the spleen and thymus of Foxp3Cre/+; Rosa26Zsgreen/+ mouse, while tdTomato(red) expression can not be detected.
Fig3. Flow cytometry analysis of zsGreen expression in the Foxp3+ cell derived from the thymus of mice. ZsGreen+ cells accounted for 37.56% of Foxp3+ cells in the thymus of Foxp3Cre/+; Rosa26Zsgreen/+ mouse.
Fig4. Flow cytometry analysis of zsGreen expression in the Foxp3+ cell derived from the spleen of mice. Zsgreen+ cells accounted for 84.74% of Foxp3+ cells in the spleen of Foxp3Cre/+; Rosa26Zsgreen/+ mouse.
Fig5. ZsGreen was also expressed in the mesenteric lymph nodes, pancreas and liver. There was a small amount of expression in the brain, pituitary gland, retina, lung, stomach, kidney, submandibular gland, brown fat, ovary and skin, and no expression in the heart, colon and muscle.(For more information please contact: 400-728-0660.)
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreAt GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more