Flt3-2A-DreERT2

Nomenclature

C57BL/6Smoc-Flt3em2(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190115

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Flt3

Synonyms

Flk2; Ly72; wmfl; CD135; Flk-2; Flt-3; B230315G04

NCBI ID

14255

MGI ID

95559

Ensembl ID

ENSMUSG00000042817

Pubmed

Flt3

Human Ortholog

FLT3

Model Description

A 2A-DreERT2 expression cassette was knocked into the Flt3 gene stop codon site.
Research Application：Tool Mice

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the liver of Flt3DreERT2/+；R26tdTomato/+mouse. TdTomato+ cells (red) were colocalized with CD45+ cells (green) in the liver of Flt3DreERT2/+；R26tdTomato/+ mouse after tamoxifen treatment. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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