Lrat-2A-Cre
Nomenclature
C57BL/6Smoc-Lratem1(2A-Cre)Smoc
Cat. NO.
NM-KI-190097
Strain State
Repository Live
Gene Summary
Gene Symbol
Lrat
Model Description
Validation Data
Fig1. Expression Pattern of tdTomato in LratCre/+ ; Rosa26tdTomato/+ mice.
Cre mediated recombination in liver nonparenchymal cells of LratCre/+ ; Rosa26tdTomato/+ mice. This strain represents an effective tool for generating liver nonparenchymal cells specific targeted mutants.
Fig2. Validation of tdTomato expression by fluorescence assay.
The liver nonparenchymal cells of Lrat-Cre mice were detected by fluorescence.
Fig. 3 Detection of tdTomato(red) in various tissues of LratCre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the heart, liver, lung, stomach, uterus, colon, intestine, muscle and spleen. Tdtomato can not be detected in the retina, brown fat, submandibular gland or thymus. (For more detailed information please contact our technical advisor.)
Publications
Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
References：Cell Metabolism
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